日本无限资源_福禄影院午夜伦_美国av毛片_亚洲自拍在线观看_激情亚洲一区国产精品_999久久久久

Chinese scientists find how bats carry viruses without getting sick

Source: Xinhua| 2018-02-23 02:02:19|Editor: Liu
Video PlayerClose

WASHINGTON, Feb. 22 (Xinhua) -- Chinese scientists have identified the secret of bats that harbor highly pathogenic viruses like Ebola, Marburg and SARS coronavirus but do not show clinical signs of disease.

In a paper published on Thursday in the journal Cell Host & Microbe, scientists at the Wuhan Institute of Virology in China find that in bats, an antiviral immune pathway called the STING-interferon pathway is dampened, so bats can maintain just enough defense against illness without triggering a heightened immune reaction.

"We believe there is a balance between bats and the pathogens they carry," said the paper's senior author Zhou Peng.

"This work demonstrated that in order to maintain a balance with viruses, bats may have evolved to dampen certain pathways," Zhou said.

According to researchers, in humans and other mammals, an immune-based over-response to one of these and other pathogenic viruses can trigger severe illness. For example, in humans, an activated STING pathway is linked with severe autoimmune diseases.

"In human history, we have been chasing infectious diseases one after another," said Zhou, "But bats appear to be a 'super-mammal' to these deadly viruses."

By identifying a weakened but not defunct STING pathway in bats, researchers have some new insight into how bats fine-tune antiviral defenses to balance an effective, but not an overt, response against viruses.

They hypothesize that this defense strategy evolved as part of three interconnected features of bat biology: they are flying mammals, have a long lifespan, and host a large viral reservoir.

"Adaptation to flight likely caused positive selection of multiple bat innate immune and DNA damage repair genes," Zhou said.

These adaptations may have shaped certain antiviral pathways including STING, interferon to make them good viral reservoir hosts and achieve a tolerable balance.

Zhou told Xinhua that the study has provided a possibility that people can learn from bats in combating virus although whether this mechanism can be directly used in humans is still unknown.

TOP STORIES
EDITOR’S CHOICE
MOST VIEWED
EXPLORE XINHUANET
010020070750000000000000011100851369923091
主站蜘蛛池模板: 欧美日产一区二区三区在线观看 | 免费人成网站www | 米奇影视四色777 | 美国超碰在线 | 亚洲天堂av网站 | 欧美激情成人在线 | 男变身成少妇h | 村女艳史理伦一及毛片 | www.se婷婷 | 激情视频91 | 91在线观看高清视频 | 亚洲精品无码成人A片蜜臀 国产精品久久丫 | 国产麻豆乱子伦午夜视频观看 | 91在线免费公开视频 | 综合久久亚洲 | 人妻少妇被粗大爽.9797pw | 尤物久久av一区二区三区亚洲 | 男人操女人视频免费观看 | 他掀开裙子舌头伸进去在线观看 | 91精品一区二区三区蜜臀 | 手机在线视频福利 | 色99热久久偷拍 | 久久综合精品国产丝袜长腿 | 成A人影片免费观看日本 | 成人福利热舞hd | 蜜桃精品成人影片 | 久久精品亚洲精品国产欧美 | 欧日韩精品 | 老司机午夜在线视频 | 99久久免费国产精品四虎 | 国产精品168 | 成人国产精品入口免费视频 | 国产精品夜夜嗨 | 99re66在线观看精品免费 | 亚洲欧美日韩成人综合一区 | 草草视频在线免费观看 | 第一会所亚洲精品无码Av | 已婚丰满少妇21P | 亚洲av无码不卡无码国产 | 九九九在线观看 | 午夜高清福利 |